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Vitamin E tied to higher risk of prostate cancer

维生素E跟患前列腺癌的高风险有關

 

Men taking daily vitamin E were more likely to get prostate cancer than those not taking the dietary supplement, according to a study of close to 35,000 North Americans.

每日服用维生素E的男性比那些不服用膳食补充剂的人更容易患上前列腺癌,这是根据一项有三万五千名北美人参与的研究所发现的。

This means that over a decade, one or two men out of 100 taking vitamin E would be expected to get prostate cancer, said the researchers, whose findings were published in the Journal of the American Medical Association.

研究员说,这就表示了十多年来,每一百位服用维生素E的男性中有一两位会患上前列腺癌,这项研究结果已经在在美国医学协会杂志上发表。

“If you have enough of these vitamins in your system…extra doesn’t help you any, and too much of something like this can be harmful,” said Eric Klein from the Cleveland Clinic, one of the study’s authors, to Reuters Health.

其中一位来自Cleveland诊所的报告书作者之一的Eric Klein对路透社健康版的记者说,“如果你体内的系统已经有足够的维生素,再多一些是一点助益也没有,而且太多的话还可能对你有害。”

The findings come on the heels of a study suggesting that older women who take multivitamins have slightly increased death rates compared to those who don’t.

这项研究也证实了另一项研究的觀點認為,吃多种维生素合成药剂的年长妇女的死亡率比起那些不吃的人来得高。

“There’s a theme here that taking vitamins is not only not helpful but could be harmful” in people who are not deficient in vitamins, Klein added.

Klein说:“这里的主题是说,服用合成维生素药丸对那些不缺维生素的人不但没有帮助而且还可能有害。”

But one researcher who wasn’t part of the new study said he doubted it means vitamin E causes prostate cancer.

但是,有一位不属于这项研究的研究员说,他很怀疑这项研究可以断定维生素E会导致前列腺癌。

“It’s an interesting finding. I’m not sure I believe it,” said Neil Fleshner, from the University of Toronto, adding that the result may have been a chance finding or false positive.

来自多伦多大学的Neil Fleshner说,“这是个有趣的发现,但我不确定要不要相信。”他补充说,这项研究结果还是有可能是个案的假象。

For the study, men in the United States, Canada and Puerto Rico were randomly assigned to one of four groups. Starting between 2001 and 2004, about 9,000 men in each group took daily supplements of 400 international units (IU) of vitamin E, 200 micrograms of selenium, vitamin E and selenium together or a vitamin-free placebo pill.

这项研究随机地把来自美国,加拿大和波多黎各的男性分配到四个小组,从2001到2004年间,每一组都有九千多人每天吞食有四百个国际单位(IU)的维生素E合成药丸,两百微克的

200微克的硒,维生素E和硒一起吃或者没有维生素的安慰剂药丸。

The study was halted in late 2008 when the researchers saw a hint of an increased risk of prostate cancer in the men taking vitamin E. But they kept monitoring men for cancer after they stopped taking the supplements. It turned out that the extra risk became clearer over time.

到了2008年年尾,研究员看到服用维生素E的男性患上前列腺癌的风险有增加的迹象时,这项研究马上终止,但他们继续观察患癌的人在停止服用补充剂后的状况,结果时日一久风险就越明显。

By mid-2011, about seven percent of men who had taken vitamin E only had gotten prostate cancer, compared to six percent of those assigned to placebo pills.

2011年年中,只有大约7%吃过维生素E药丸的人已经得到前列腺癌,而分配到安慰剂药丸的人患癌的有6%。

The researchers did not find an extra risk of prostate cancer in men who took only selenium or vitamin E together with selenium.

研究员并没有发现那些只吃硒或维生素E与硒一起吃的的男性有患上前列腺癌的的额外风险。

Klein and his colleagues said it’s not clear how vitamin E would increase the risk of prostate cancer, and that not all past studies have shown it does any harm to the prostate. Some have even found a lower prostate-cancer risk with vitamin E.

Klein和他的同事们说,目前还不清楚维生素E是如何会增加患前列腺癌的风险,但并不是所有以前的研究都显示对前列腺有害,有些人甚至发现维生素E使到患前列腺癌的风险降低。

He added that the new findings aren’t definite proof that vitamin E causes extra prostate cancers, but that there wasn’t anything else that could explain why men taking the vitamin were more likely to be diagnosed with cancer — for example, they weren’t screened more frequently.

他补充说,这个新发现并没有明确地证明维生素E会产生多余的前列腺癌细胞,但也没有其他理由可以解释为什么服用维生素的男性更容易被诊断出致癌—譬如说,他们并没有接受很多次的断层扫描。

The supplement doses, he added, are much higher than what’s in most over-the-counter multivitamins, which typically contain 15 to 25 IU of vitamin E.

他接着说,补充剂量比起大多数的柜台在卖的多种维生素药丸还高得多,都有15至25 IU的维生素E成份在内。

Fleshner said that either way, vitamin E doesn’t seem to be beneficial for prostate health.

Fleshner说,无论是哪一种吃法,维生素E似乎都对前列腺的健康没有好处。

“There’s certainly no major evidence that vitamin E helps, so why bother?” he said.

他说,“当然也没有主要的证据显示维生素E对健康有益,那又何必管是怎么个吃法?”

While vitamin supplements are known to prevent disease in people who have vitamin deficiencies, so far studies haven’t found much extra benefit in people who already get enough vitamins through their diet. Specifically, vitamin E has not been shown to protect against heart disease, colon cancer or lung cancer.

大家都知道维生素补充剂是用来防止缺维生素的人患病,到目前为止,各项研究并没有发现在食谱中摄取足够维生素的人有得到更多的好处,特别是维生素E并没有显示出能有效防止心脏病,结肠癌或肺癌。

On the other hand, there is a growing body of evidence suggesting supplements may be harmful in high doses.

另一方面,有越来越多的证据在暗示剂量太多可能对身体有害。

“Vitamins are not innocuous substances,” Klein said.

Klein说,“维生素并不是无害的物质。”

 

—— END ——

 

Source > Reuters-路透社,October 12, 2011

Translated by > BlogHost

Word Count > approx. 600 words in English

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